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From lab to life: functional validation of AML data Understanding AML resistance is only part of the battle. Translating this knowledge into actionable therapies is where the TALETE project truly shines. By employing sophisticated in vitro models, we are validating…
Understanding AML resistance Acute Myeloid Leukemia (AML) remains one of the most challenging cancers to treat, especially in elderly patients. Resistance to treatment often stems from the bone marrow (BM) microenvironment, a complex network of immune and stromal cells that…
The immune microenvironment: a key to better treatments Immunotherapy is revolutionizing cancer treatment, but its success in AML has been limited. The TALETE project is tackling this challenge by focusing on how the immune microenvironment responds to azacitidine and venetoclax,…